If your dog suffers from anxiety aggression or obsessive compulsive disorder medication is your best bet for providing relief Clomipramine Clomicalm is a tricyclic antidepressant used primarily to treat issues caused by separation anxiety in dogs but can also be prescribed to decrease behaviors such as aggression or obsessive compulsive disorders Symptoms of OCD in dogs include tailchasing excessive grooming and more This medication can also be used to treat anxiety in cats but consult your veterinarian before administering Clomipramine as cats tend to show an increased sensitivity to this type of antidepressant